Personalized Cancer Risk Assessments for Space Radiation Exposures

Personalized Cancer Risk Assessments for Space Radiation Exposures

Individuals differ in their susceptibility to radiogenic cancers, and there is evidence that this inter-individual susceptibility extends to HZE ion-induced carcinogenesis. Three components of individual risk: sex, age at exposure, and prior tobacco use, are already incorporated into the NASA cancer risk model used to determine safe days in space for US astronauts. Here, we examine other risk f...

Nuclear Submarine Decommissioning. Radiation Risk Assessments

INTRODUCTION From a beginning of atomic shipbuilding (the 1956) in Russia built about 250 atomic submarines (NPS), 5 ships and 9 civil atomic vessels. In connection with expiry of the term of maintenance and conclusion of the contracts about limitation and cutting of offensive arms of Russia from the extremity of the 1980-th years acutely there was a problem of their utilization. Utilization of...

Personalized Risk Assessments in the Criminal Justice System

Probabilistic Radiological Risk Assessments for Radiation Facilities with Vague Information

The objectives of this article are to provide streamlined technique, including the Delphi approach, Bayesian update and two-dimensional Monte Carlo analysis(2D MCA), and to provide information through the investigation of factors in risk model which supports risk assessment for the radiological risk assessment in operation of such radiation facilities with vague information. The scope of this s...

Visualizing Personalized Cancer Risk Prediction

Cancer, as we now know, is a genetic disease. This knowledge entails that to enable evidence-based personalized diagnosis for any patient, the location of where the tumor occurs (e.g. brain, liver, etc.) is less relevant than the underlying genetic signature that the cancer cells express (i.e. whether genes are silenced, amplified or mutated). With the advent of high-throughput gene sequencing ...